Learning Outcomes

Identify the various components of the lymphatic system.
Describe the structure and function of important lymphatic vessels.
Describe the lymph-collecting vessels, and explain lymphedema.
Identify the classes of lymphocytes, discuss their importance, and describe their distribution in the body.
Describe lymphoid tissues, and trace lymph flow through a lymph node.
Describe the structure and function of the thymus.
Describe the structure and function of the spleen, and trace blood flow through it.
Give an overview of the components of innate (nonspecific) immunity.
Explain how physical barriers play a role in innate immunity.
Explain the role phagocytes play in innate immunity.
Describe immune surveillance, and explain the role of NK cells.
Describe the types of interferons, and explain the pathways of complement activation.
Explain the significance of inflammation and fever as innate defense mechanisms.
Describe the types of adaptive immunity and four properties of adaptive immunity.
Explain how antigens trigger an immune response.
Explain the events of antigen recognition and the roles of CD markers in T cell differentiation.
Explain the sensitization and activation of B cells and the role of plasma cells.
Describe the structure of an antibody, discuss the types of antibodies, and explain the primary and secondary responses to antigen exposure.
Explain the mechanisms by which antibodies destroy target antigens.
Explain hypersensitivities, anaphylaxis, and the role of antibodies in each.
Summarize the integration of innate and adaptive immunity.
Explain autoimmune disorders, transplant rejection, and immunodeficiency diseases, and describe age-related changes in the immune response.

Lymphatic Structures Notes (PDF)

Immunity Notes (PDF)

Part 1

Part 2

Part 3

Part 4